Over the years of my being a Christian, I have probably prayed Psalm 43:3-4 (with varying slight modifications) many hundreds of times before studying the Bible:
O send out Thy light and Thy truth: let them lead me; let them bring me unto Thy holy hill, and to Thy tabernacles. Then will I go unto the altar of God, unto God my exceeding joy: yea, upon the harp will I praise thee, O God my God.
I can attest to God’s having answered that prayer numerous times by granting me insight into many passages, even passages that I had previously studied many times in the past. Because I believe that the Bible is an infinite book, I believe that we should expect God, as He sees fit, to show us wondrous things that we have not seen before, even from familiar passages.
I encourage you to believe in a similar manner and expect God to answer such prayers for you as well.